Deutsche medizinische Wochenschrift
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Pancreatic cancer is still associated with a poor prognosis and remains the fourth leading cause of cancer related mortality. Overall, long-term survival is about 5 %. However, when pancreatic cancer can be resected, five-year survival rates increase to approximately 25 %. ⋯ Often, these tumors are diagnosed in premalignant or early invasive stages. While the outcome of late tumor stages of cystic and ductal pancreatic carcinomas is identical to ductal adenocarcinomas, the long-term outcome of prophylactic resection of premalignant or resection of early tumor stages of cystic tumors is excellent. Thus, early surgical treatment must be considered in cystic pancreatic tumors.
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Dtsch. Med. Wochenschr. · Sep 2011
[Peritoneal carcinomatosis of colorectal cancer: cytoreductive surgery and hyperthermic intraperitoneal chemotherapy].
Peritoneal carcinomatosis caused by colorectal carcinoma is still considered as the end-stage of disease. A multi-modal therapeutic concept including maximal cytoreduction followed by intraperitoneal hyperthermic chemotherapy (HIPEC) has the potential to cure selected patients. In case of peritoneal carcinomatosis palliative systemic treatment is no longer the state of the art. This article addresses aspects of the disease, the rationale behind peritonectomy with HIPEC, and the surgical management of peritoneal carcinomatosis.