Deutsche medizinische Wochenschrift
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Dtsch. Med. Wochenschr.
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Dtsch. Med. Wochenschr. · Jul 2011
Review[ADP receptor blockers: new insights in the therapy and prophylaxis of ischemic heart disease].
Adenosine diphosphate (ADP)-induced platelet activation plays a pivotal role in the thrombocyte aggregation and pathogenesis of ischemic heart disease. The long-term benefit of dual anti-platelet therapy with ADP-receptor antagonists, such as clopidogrel, in combination with aspirin is well established for patients following coronary stent implantation. This review discusses latest developments in the field of ADP-receptor antagonists.