Ophthalmic surgery and lasers
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Ophthalmic Surg Lasers · Mar 1999
Randomized Controlled Trial Comparative Study Clinical TrialApraclonidine 0.5% versus brimonidine 0.2% for the control of intraocular pressure elevation following anterior segment laser procedures.
Both apraclonidine hydrochloride 0.5% and brimonidine tartrate 0.5% are potent alpha-2 agonists, effective in controlling the intraocular pressure (IOP) rise following argon laser trabeculoplasty (ALT). Brimonidine has recently become available commercially as a 0.2% solution. Our goal in this study was to compare the efficacy and side effect profile of 0.2% brimonidine to that of 0.5% apraclonidine in the prevention of IOP spikes following anterior segment laser procedures. ⋯ Both drugs are highly effective in controlling IOP spikes following anterior segment laser procedures. There is a tendency toward higher risk of IOP rise following argon laser trabeculoplasty with 0.2% brimonidine as compared to 0.5% apraclonidine, however, this was not statistically significant.
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Ophthalmic Surg Lasers · May 1998
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialA prospective randomized trial of topical soluble 0.1% indomethacin versus 0.1% diclofenac versus placebo for the control of pain following excimer laser photorefractive keratectomy.
To compare the safety and efficacy of topical nonsteroidal antiinflammatory drugs (NSAIDs) for the control of pain after excimer laser photorefractive keratectomy (PRK). ⋯ Topical 0.1% indomethacin solution helps control the pain induced by excimer laser photoablation of the cornea without any detrimental effect to the corneal epithelial wound healing.
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Ophthalmic Surg Lasers · Mar 1998
Randomized Controlled Trial Clinical TrialOculocardiac reflex during retinal surgery using peribulbar block and nitrous narcotic anesthesia.
This study was designed to examine the effects of local and general anesthesia on the oculocardiac reflex (OCR) in adults during retinal detachment surgery, with an aim of determining the safest type of anesthesia and on which extraocular muscle traction causes a higher incidence of OCR. ⋯ This study showed that local anesthesia produces less bradycardia and ectopic arrhythmias and, therefore, may be safer and better than general anesthesia for surgeries in which traction of extraocular muscles is required.
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Ophthalmic Surg Lasers · Dec 1997
Randomized Controlled Trial Comparative Study Clinical TrialInjectable centbucridine and lidocaine hydrochloride for intraocular surgery.
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Ophthalmic Surg Lasers · Dec 1997
Randomized Controlled Trial Clinical TrialPostoperative miotics for patients with infantile esotropia.
To examine the postoperative effect of echothiophate iodide in children who underwent surgery to congenital esotropia, and to find out whether it significantly reduced the residual esotropia. ⋯ Echothiophate iodide, given postoperatively for congenital esotropia, does not improve the surgical results during the first postoperative year.