Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine
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Aviakosm Ekolog Med · Mar 2009
Comparative Study[Determination of ion content and localization of vasopressin and aquaporin receptors in the gerbil kidney after the flight aboard biosatellite "Foton M3"].
After 12 days on space fight, body mass of gerbils decreased by 32.9%; however, the effective systems of regulation did not let changes in the concentration of Na, K, Mg ions in fresh samples of the renal cortex. These data are viewed as a reflection of the regulation systems strategy to preserve the optimal conditions for functioning of the kidney, a vital body organ. ⋯ This could have changed the osmoregulating function of the kidney during space fight and, due to small cations accumulation, caused the drop of the cortex/medulla osmotic gradient. Locations of V1a-, V1b- and V2-receptors and aquaporin 1 and 2 in renal tubule cells of gerbils before and fight are described.