Diabetes technology & therapeutics
-
Diabetes Technol. Ther. · Feb 2014
Randomized Controlled TrialAccuracy of subcutaneous continuous glucose monitoring in critically ill adults: improved sensor performance with enhanced calibrations.
Accurate real-time continuous glucose measurements may improve glucose control in the critical care unit. We evaluated the accuracy of the FreeStyle(®) Navigator(®) (Abbott Diabetes Care, Alameda, CA) subcutaneous continuous glucose monitoring (CGM) device in critically ill adults using two methods of calibration. ⋯ Accuracy of the Navigator CGM device during critical illness was comparable to that observed in non-critical care settings. Further significant improvements in accuracy may be obtained by frequent calibrations with ABG measurements.
-
Diabetes Technol. Ther. · Feb 2014
Poor agreement of computerized calculators for mean amplitude of glycemic excursions.
Glucose variability has been identified as a predictor of hypoglycemia and has been associated with mortality in critically ill patients without diabetes. A popular metric to quantify glucose variability is the mean amplitude of glycemic excursions (MAGE). The "ruler and pencil" approach to calculate MAGE is operator-dependent and time-consuming for analysis of continuous glucose monitoring data. Therefore, several computer software programs have been developed for the automated calculation of MAGE. The aim of our study was to evaluate the agreement of currently available MAGE calculators when applied to the same set of continuous glucose monitoring (CGM) traces. ⋯ Available computer programs developed to calculate MAGE show varying agreement. Although software programs for the calculation of MAGE would seem attractive to assess glucose variability, their use has limitations by different outcomes, in the absence of a gold standard.