Magyar onkologia
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The purpose of the study is to report the status of Hungarian radiotherapy (RT) based on the assessment of treatment data in years 2012 to 2014, available infrastructure, and RT staffing. Between December 2014 and January 2015, a RT questionnaire including 3 parts (1. treatment data; 2. infrastructure; 3. staffing) was sent out to all Hungarian RT centers (n=12). All RT centers responded to all questions of the survey. 1. ⋯ Brachytherapy and modern teletherapy (e.g. IMRT and IGRT) are underutilized in Hungary compared to other European countries. Implementation of continuous education and practical training programs in leading Hungarian and international RT centers are suggested in an effort to a wider implementation of modern RT techniques in Hungarian RT centers.
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Comparative Study
[Dosimetry analysis of intensity-modulated and conformal radiation therapy for head and neck tumors].
The aim of the study was to compare different treatment plans - intensity-modulated and conformal - for head and neck cancer patients. Treatment plans were developed for ten head and neck cancer patients by applying four different techniques: two conventional 3D conformal plans (forward treatment planning, with two opposing fields 90o-270o and one asymmetric anterior field, matching in isocenter /Conv/, conformal parotis sparing plans /ConPas/), 3D conformal plans with inverse treatment planning techniques /INVCRT/ and intensity-modulated radiation therapy plans /IMRT/. The plans were made for the same target volumes PTV50 (elective) and PTV66 (boost-16 Gy). ⋯ Although the sparing of the oral cavity was the most effectively provided by the traditional technique - due to the arrangement of the fields - it gave the worst results regarding the parotis and the target volume. The highest dose for the oral cavity was given by the ConPas technique, which can cause serious early and late side effects. By increasing the number of segments for IMRT at a reasonable level, the dose for OARs can be reduced.
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The purpose of our work was to compare intraoperative and four-week post-implant dosimetry for loose and stranded seed implants for permanent prostate implant brachytherapy. In our institute low-dose-rate (LDR) prostate brachytherapy is performed with encapsulated I-125 isotopes (seeds) using transrectal ultrasound guidance and metal needles. The SPOT PRO 3.1 (Elekta, Sweden) system is used for treatment planning. ⋯ The dose coverage of the target decreased significantly at four-week plans for both techniques. The decrease was larger for LS technique, but the difference between techniques was not significant at this patient number. The dose distribution was more homogenous, but the conformality was worse at four-week plans.
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The purpose of the study was to implement accelerated partial breast irradiation (APBI) by means of image-guided intensity-modulated radiotherapy (IG-IMRT) following breast-conserving surgery (BCS) for low-risk early invasive breast cancer. Between July 2011 and March 2014, 60 patients with low-risk early invasive (St I-II) breast cancer who underwent BCS were enrolled in our phase II prospective study. Postoperative APBI was given by means of step and shoot IG-IMRT using 4 to 5 fields to a total dose of 36.9 Gy (9×4.1 Gy) using a twice-a-day fractionation. ⋯ Excellent and good cosmetic outcome was detected in 45 (75%) and 15 (25%) patients. IG-IMRT is a reproducible and feasible technique for the delivery of APBI following conservative surgery for the treatment of low-risk, early-stage invasive breast carcinoma. Preliminary results are promising, early radiation side effects are minimal, and cosmetic results are excellent.