Pain medicine : the official journal of the American Academy of Pain Medicine
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To investigate the efficacy of repeated application of capsaicin 179 mg cutaneous patch in nonresponders to the first application. ⋯ Although some patients with peripheral neuropathic pain experience rapid improvements with a single treatment of capsaicin 179 mg patch, some may require two or three treatments before an initial response is observed. Similar benefits for pain, sleep, and QOL can be achieved in early and late responders.