Clinical & experimental ophthalmology
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Clin. Experiment. Ophthalmol. · Apr 2014
Long-term efficacy and safety of botulinum toxin A injections to treat blepharospasm and hemifacial spasm.
To evaluate efficacy and safety of botulinum toxin A injections after more than 10 consecutive years of treatment for benign essential blepharospasm and hemifacial spasm. ⋯ Botulinum toxin A is an effective, safe, long-term treatment for patients with benign essential blepharospasm and hemifacial spasm. Sustained treatment efficacy required higher doses; however, fewer adverse reactions developed.