São Paulo medical journal = Revista paulista de medicina
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Randomized Controlled Trial Clinical Trial
Effects of ondansetron on respiratory pattern and sensation of experimentally induced dyspnea.
Dyspnea remains a therapeutic challenge, especially in chronic respiratory conditions. Recent studies have shown that the induction of unpleasant dyspnea sensations activates areas in the insular cortex. ⋯ The present results suggest that 5-HT3 receptors do not play an important role in the mediation of dyspnea sensations.