Sleep medicine
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Randomized Controlled Trial Multicenter Study
Evaluation of subjective efficacy and safety of ramelteon in Japanese subjects with chronic insomnia.
To assess patient-reported efficacy and safety of ramelteon in Japanese patients with chronic insomnia. ⋯ In Japanese adults with chronic insomnia, ramelteon 8 mg significantly reduced patient-reported sleep latency, increased total sleep time and improved sleep quality after 1 week of treatment. Ramelteon was generally well tolerated with no rebound insomnia.