Current opinion in allergy and clinical immunology
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Curr Opin Allergy Clin Immunol · Feb 2011
ReviewBacterial biofilms and the pathophysiology of chronic rhinosinusitis.
To review the evidence for the presence of bacterial biofilms in chronic rhinosinusitis (CRS) and mechanisms by which they may contribute to the chronic inflammation characteristic of this disease. Lastly, to provide an overview of the current and potential future treatments for bacterial biofilms in CRS. ⋯ Biofilms represent an important influence on the pathophysiology of CRS. Further understanding of biofilm interactions and microbial organism behavior will provide us with future treatment modalities for this disease.