Pain physician
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Review Meta Analysis
Efficacy of Palmitoylethanolamide for Pain: A Meta-Analysis.
Palmitoylethanolamide (PEA) is a cannabimimetic compound that has been investigated as an analgesic agent in animal models and clinical trials. ⋯ PEA, palmidrol, palmitoylethanolamide, efficacy, pain, pain management, meta-analysis.
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Review Case Reports
Percutaneous Vertebroplasty for Primary Non-Hodgkin's Lymphoma of the Thoracic Spine: Case Report and Review of the Literature.
Primary non-Hodgkin's lymphoma of the vertebra is rare in the spine of the elderly. The clinical presentation and radiological features are unspecific, which make it more difficult for diagnosis. We report a case of a 79-year-old woman complaining of serious backache without any injury. ⋯ The patient was diagnosed with primary bone lymphoma finally. Due to the previous condition of the patient, R-miniCHOP chemotherapy was applied following the surgery in the department of hematology. Until the 9 months follow-up, the clinical result was still satisfactory.
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Refractive surgery is a common procedure, but may be associated with severe post-operative pain. ⋯ Photorefractive keratectomy, in situ keratomileusis, pain, analgesia, opioid, codeine, review.
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Review Meta Analysis
High Prevalence of Neuropathic Pain Component in Patients with Low Back Pain: Evidence from Meta-Analysis.
Low back pain (LBP) is a complex syndrome which includes a nociceptive (NcP) component, a neuropathic (NeP) component, or a mixture of components (mixed pain). The NeP component (NePC) in LBP is defined as the presence of NeP with or without an NcP. ⋯ Neuropathic pain, nociceptive pain, low back pain, symptom-based questionnaire, chronicity.
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Research into interventional techniques in managing chronic spinal pain continues to be challenging, mystifying, confusing, and biased. Insight, or lack thereof, into placebo and nocebo phenomena contributes mightily to these difficulties. Unfortunately, placebo-nocebo responses are the subject of numerous controversies and challenges from not only a research perspective, but also clinical perspective. ⋯ This review focuses on a multitude of controversies surrounding placebo and nocebo phenomena in research and clinical applications. The discussion includes a focus on unsolved, forgotten, and ignored features of placebo responses in medicine, and provides an appropriate understanding of placebo and nocebo phenomena in interventional pain management. To that effect, this review also describes therapeutic placebos, research with open placebos, and improvements in understanding clinical applications of present interventional pain management research.