Pain physician
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Recently, denervation therapy has been applied clinically for the treatment of intractable osteoarthritis (OA). This therapy provides an alternative for patients who are insensitive to conservative therapies or unwilling to receive surgery and general anesthesia. However, therapeutic effect of this method, especially the long-term efficacy, is still controversial. ⋯ Osteoarthritis, denervation therapy, radiofrequency, chronic pain, function, systematic review, meta-analysis.
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Anterior cervical discectomy, with or without interbody fusion, is a common technique to treat cervical spondylotic myelopathy (CSM). To date, controversy still exists among spine surgeons regarding the anterior surgical approach to be used for the treatment of multilevel CSM. ⋯ Multilevel cervical spondylotic myelopathy, anterior cervical discectomy and fusion, anterior cervical corpectomy and fusion, cervical total disc replacement, hybrid surgery, effectiveness, safety, network meta-analysis.
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Meta Analysis
Percutaneous Endoscopic Debridement and Drainage for Spinal Infection: Systemic Review and Meta-Analysis.
Percutaneous endoscopic debridement and drainage (PEDD) has played a vital role in the management of spinal infection; however, limited PEDD results are available to date. ⋯ Percutaneous endoscopic debridement and drainage, spinal infection, meta-analysis.
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Meta Analysis
The Relevance of the OPRM1 118A>G Genetic Variant for Opioid Requirement in Pain Treatment: A Meta-Analysis.
There is obvious difference in individual response to opioids. Many studies have examined the correlation between the mu-opioid receptor 1 (OPRM1) 118A>G genetic variation and opioid requirement in pain treatment, but the conclusion remains elusive. ⋯ OPRM1, genetic variation, opioid, pain, side effect, review, meta-analysis.