Journal of virology
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Journal of virology · Jan 1993
Comparative StudyBorna disease virus in mice: host-specific differences in disease expression.
We developed a mouse model of Borna disease to facilitate immunopathogenesis research by adaptation of Borna disease virus to mice through serial passage in mouse brain tissue. Borna disease virus replication, antibody production, inflammation, and Borna disease expression in several different strains of mice were examined.