The lancet oncology
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The lancet oncology · Jul 2022
Association of tobacco control measures with the intention to quit tobacco consumption: a cross-sectional study from India.
More than 7 million cancer-related deaths worldwide are associated with tobacco, of which India is the second largest producer and consumer. The current study tests a model based on the hypothesis that poor implementation of tobacco control measures and poor basic education affect the frequency and duration of tobacco use, creating substantial nicotine dependency and thereby preventing smokers from quitting tobacco consumption. ⋯ None.
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The lancet oncology · Jul 2022
Observational StudyFeasibility of self-sampling and human papillomavirus testing in rural and urban areas for cervical cancer prevention in Bolivia: an observational study.
Cervical cancer is a major health problem in Latin America. In 2019, the Italian Agency for Development Cooperation (La Paz regional site) conducted a pilot study to estimate the prevalence of high-risk human papillomavirus (HPV) and the feasibility of HPV screening in Bolivia through self-sampling and portable and transportable laboratory instruments for HPV testing in urban and rural areas. ⋯ Italian Agency for Development Cooperation (Italian Ministry of Foreign Affairs), as a part of an ongoing technical assistance programme with the Bolivian Ministry of Health.
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The lancet oncology · Jul 2022
Discordance between clinical and post-surgical staging of patients with operable non-small cell lung cancer: a retrospective audit of lung cancer surgery with curative intent from a single pathology practice.
Clinical staging of non-small cell lung cancer (NSCLC) by CT and PET, with or without endobronchial ultrasound-guided transbronchial needle aspiration of lymph nodes (EBUS-TBNA), is essential for prognostication and to direct treatment. Clinical understaging can lead to inappropriate radical excision of the primary tumour with no clinical benefit, whereas overstaging might deprive patients of beneficial or potentially curable treatments. Although not widely documented, several reports have indicated a suboptimal concordance between clinical and post-surgical staging. This study has investigated the incidence of discordance between clinical and post-surgical staging of operable NSCLC cases evaluated at PathWest Fiona Stanley Hospital (Perth, WA, Australia). ⋯ OT is the recipient of a student scholarship from the Royal College of Pathologists of Australasia that funded this work.
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The lancet oncology · Jul 2022
Prognostic factors in curative intent stage I lung adenocarcinoma: a retrospective hospital-based cohort study.
Radiotherapy or surgery, depending on hospital specialisation status (ie, High Complexity Centres in Oncology [HCCO; hospitals with infrastructure, technology, physical facilities, equipment, and human resources suitable for highly complex specialised assistance], or Partial Hospital Complexity Centres in Oncology [PHCCO; hospitals with infrastructures and specialisation similar to that of HCCOs, but doing diagnosis and treatment for common cancers only], as per nomenclature used in Brazil), can increase overall survival in patients diagnosed with lung adenocarcinoma. However, many patients do not accept surgery because of comorbidities and personal preferences. In addition, the long time between diagnosis and treatment and the qualification of the hospital specialisation status might affect the outcomes for patients with lung adenocarcinoma. The aim of this study was to evaluate prognostic factors of overall survival in patients with stage I lung cancer adenocarcinoma diagnosed in the state of São Paulo, Brazil. ⋯ Oncocentro Foundation and Hospital Alemão Oswaldo Cruz, São Paulo, Brazil.
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The lancet oncology · Jul 2022
CK2α as a prognostic factor in invasive ductal carcinomas of the breast: cancer recurrence prognosis by surgical sampling.
Breast cancer is the most common cancer in Japanese and Asian women. Although the 5-year survival rate of these patients is relatively high, recurrences and fatalities do occur. The objective of this work was to develop a reliable prognostic indicator to guide therapeutic intervention without waiting for recurrence or metastasis. ⋯ Japan Agency for Medical Research and Development (grant number 20lm0203006j0004).