The lancet oncology
-
The lancet oncology · Jul 2022
Discordance between clinical and post-surgical staging of patients with operable non-small cell lung cancer: a retrospective audit of lung cancer surgery with curative intent from a single pathology practice.
Clinical staging of non-small cell lung cancer (NSCLC) by CT and PET, with or without endobronchial ultrasound-guided transbronchial needle aspiration of lymph nodes (EBUS-TBNA), is essential for prognostication and to direct treatment. Clinical understaging can lead to inappropriate radical excision of the primary tumour with no clinical benefit, whereas overstaging might deprive patients of beneficial or potentially curable treatments. Although not widely documented, several reports have indicated a suboptimal concordance between clinical and post-surgical staging. This study has investigated the incidence of discordance between clinical and post-surgical staging of operable NSCLC cases evaluated at PathWest Fiona Stanley Hospital (Perth, WA, Australia). ⋯ OT is the recipient of a student scholarship from the Royal College of Pathologists of Australasia that funded this work.
-
The lancet oncology · Jul 2022
Feasibility of human papillomavirus self-sampling to combat COVID-19-related disruptions to cervical cancer screening: a cross-sectional survey.
The prevalence of human papillomavirus (HPV) infection among Chinese women in Hong Kong has been reported to range between 7% and 11%, and high-risk HPV genotypes accounted for about 90% of cases of cervical cancer. The COVID-19 pandemic has had a major impact on a wide range of health outcomes because of limitations to the functioning of health services, including cervical cancer screening. The aim of this study was to assess HPV self-sampling as an alternative option for cervical cancer screening during the COVID-19 pandemic. ⋯ This study was supported by the Commissioned Health and Medical Research Fund of Food and Health Bureau of HKSAR Government (reference number CID-CUHK-E).
-
The lancet oncology · Jul 2022
Observational StudyFeasibility of self-sampling and human papillomavirus testing in rural and urban areas for cervical cancer prevention in Bolivia: an observational study.
Cervical cancer is a major health problem in Latin America. In 2019, the Italian Agency for Development Cooperation (La Paz regional site) conducted a pilot study to estimate the prevalence of high-risk human papillomavirus (HPV) and the feasibility of HPV screening in Bolivia through self-sampling and portable and transportable laboratory instruments for HPV testing in urban and rural areas. ⋯ Italian Agency for Development Cooperation (Italian Ministry of Foreign Affairs), as a part of an ongoing technical assistance programme with the Bolivian Ministry of Health.
-
The lancet oncology · Jul 2022
Cancer registry operations in the Caribbean during the COVID-19 pandemic: a report of lessons learned and opportunities identified to support strong and sustainable health systems.
Population-based cancer registries (PBCRs) are crucial for cancer prevention and control planning. Building and maintaining resilient information systems within cancer registries that enable consistent and uninterrupted operations during public health emergencies is important. We report on the impact of the COVID-19 pandemic on the operations of Caribbean PBCRs, together with opportunities, lessons learned, and strategies to strengthen and sustain PBCR operation and data quality. ⋯ Financial support for the Hub is provided by the Caribbean Public Health Agency and the US National Cancer Institute, with in-kind support from International Agency for Research on Cancer, the North American Association of Central Cancer Registries, and the US Centers for Disease Control and Prevention. Caribbean PBCRs are funded by their respective Governments. This work received no specific funding.
-
The lancet oncology · Jul 2022
CK2α as a prognostic factor in invasive ductal carcinomas of the breast: cancer recurrence prognosis by surgical sampling.
Breast cancer is the most common cancer in Japanese and Asian women. Although the 5-year survival rate of these patients is relatively high, recurrences and fatalities do occur. The objective of this work was to develop a reliable prognostic indicator to guide therapeutic intervention without waiting for recurrence or metastasis. ⋯ Japan Agency for Medical Research and Development (grant number 20lm0203006j0004).