The lancet oncology
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The lancet oncology · Jul 2022
Associations between long-term exposure to wildfire-related particulate matter and site-specific cancer mortality: a national study in Brazil, 2010-16.
With the increasing frequency and duration of wildfires over the past 10 years, the effects of wildfire on health need to be better understood. Long-term exposure to particulate matter less than 2·5 μm in diameter (PM2·5) has been linked to cancer mortality. However, the long-term effects of wildfire-related PM2·5 exposure on cancer mortality risk were unknown. The aim of this study was to assess the association between wildfire-related PM2·5 and cancer mortality in Brazil on the basis of nationwide death records for the period of 2010-16. ⋯ Australian Research Council and National Health & Medical Research Council; China Scholarship Council.
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The lancet oncology · Jul 2022
Current public perception of, and barriers to, palliative care in China: a mixed-methods study.
Cancer is a major cause of death in China, accounting for 2·56 million deaths in the country in 2018 alone. Yet, on that year, only 28 600 patients (1·1%) at the end of life received palliative care. Existing studies in palliative care have mainly been done in medical environments. The aim of this study was to focus instead on the general public and to identify the public's perceptions of, and demand for, various palliative care services, as well as barriers to palliative care in China. ⋯ Ministry of Education of China, Youth Project of Humanities and Social Sciences (project number 20XJC840001); China Postdoctoral Science Foundation (project number 2021M691521); and 2020 Young Teacher Development Project of the Chinese Universities Scientific Fund (project number 230600001002020030).
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The lancet oncology · Jul 2022
Observational StudySalivary and tumour tissue miR-21 for prediction of cervical lymph node metastasis in patients with oral squamous cell carcinoma: an observational study.
Oral squamous cell carcinoma is a substantial health burden and one of the most common cancers worldwide. 40% of patients with oral squamous cell carcinoma have metastasis to cervical lymph nodes. Modern diagnostic aids for the assessment of lymph node metastasis have some limitations and drawbacks. miR-21 targets genes associated with the metastatic process in oral squamous cell carcinoma. The aim of the study was to evaluate the sensitivity and specificity of miR-21 for the assessment of cervical lymph node metastasis in patients with oral squamous cell carcinoma. ⋯ None.
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The lancet oncology · Jul 2022
Performance of artificial intelligence-based breast cancer screening in a community setting: a real-world evaluation study.
Despite improvements in treatment strategies, breast cancer survival rates in India remain low because of poor awareness and advanced stages at presentation. Early diagnosis and treatment can improve the survival rates of patients with breast cancer. A population-based breast cancer screening programme with mammography is often not feasible in resource-constrained settings. Thermalytix, a novel breast cancer screening technology, applies artificial intelligence algorithms over thermal images to generate an automated interpretation report indicating breast health. The Thermalytix testing equipment is portable, requires minimal skills to operate, and operation is 20 times less expensive than a mammography. The test has been used to screen women in community settings in India. This study was done to assess the performance of the Thermalytix test in identifying women suspicious of breast cancer in community settings. ⋯ This programme was sponsored by Niramai Health Analytix and was executed in collaboration with National Health Mission, Maharashtra, India, and Bruhat Bengaluru Mahanagara Palike, Municipal Corporation of Bangalore City, Karnataka, India.
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The lancet oncology · Jul 2022
Excess mortality in patients with cancer during the COVID-19 pandemic in Peru: an analysis of death registry data.
The COVID-19 pandemic has had a direct effect on patients with cancer, as reflected by the large number of COVID-19-related cancer deaths reported worldwide and the substantial decrease in cancer-related consultations during the pandemic. However, the impact of the COVID-19 pandemic on cancer mortality in Latin American countries has not been properly estimated. The aim of this study was to analyse the excess mortality related to cancer during the pandemic in Peru, including deaths directly or indirectly attributed to COVID-19. ⋯ International Joint Laboratories Programme of the French National Research Institute for Sustainable Development.