Problemy e̊ndokrinologii
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Problemy e̊ndokrinologii · Nov 2019
[The frequency of formation of a motivated refusal to take androgenic anabolic steroids by men with recreational activity].
The widespread use of AAS for non-medical purposes is more than often becoming the cause of secondary hypogonadism. The study of the formation of the negative attitude towards the use of AAS among the gym visitors is quite relevant. ⋯ Individual informational interviews aimed at providing knowledge about the negative effects of steroids on the body motivated the desire to stop using them amongst 31.8% of AAS users. The obtained data points out to a developed AAS addiction which requires the involvement of psychiatrists to get rid of it.
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Problemy e̊ndokrinologii · Mar 1991
[Changes in the receptor binding of dexamethasone and insulin by blood cells in rats after hydrocortisone administration in early postnatal ontogenesis].
A study was made of the effect of hydrocortisone, administered in early postnatal ontogenesis, on insulin and glucocorticoid reception in erythrocytes and mononuclear leukocytes. Hydrocortisone was administered to rat weanlings intraperitoneally at different ages of their life (5 days, 13, 15, 17 days, 1, 2 and 3 months). It has been assumed that extensive corticosteroid therapy resulting in prolonged imbalance of the level of the adrenocortical hormones and blood insulin, changes the receptor binding of these hormones on target cells as a result of a decrease in the hormone regulated receptor pool.