Current pharmaceutical biotechnology
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Curr Pharm Biotechnol · Jan 2014
EditorialmiRNA and cancer; computational and experimental approaches.
Human genome sequencing was started to solve four letter algorithm of the genome to understand the complex nature of human metabolism. However, after completion of Human Genome Project many scientists realized that sequence information alone was not sufficient to solve the biochemical mechanism of the organism through classical approaches. Non-coding parts of the genome produce small conserved ribonucleic acids, miRNAs to control cellular and physiological processes [1, 2]. ⋯ This thematic issue presents current efforts in determination of miRNAs at different cancer types. Each day determined miRNAs are deposited to the databases and scientists give a lot of effort to understand the biogenesis of these small molecules. These scientific studies and approaches are expected to improve current technologies for therapy and biomarker detection.