Emergency medicine journal : EMJ
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Review Case Reports
BET 4: quantifying the risk of venous thromboembolism for temporary lower limb immobilisation in ambulatory patients.
A short cut review was carried out to establish whether the risk of a venous thromboembolic event could be quantified for patients with temporary immobilisation of the lower limb after injury. Five papers were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The clinical bottom line is that the incidence of venous thromboembolism following temporary immobilisation for isolated lower limb trauma in ambulatory patients is approximately 11%.
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Review Case Reports
BET 1: should tranexamic acid be given to patients who are having an upper gastrointestinal bleed?
A short cut review was carried out to establish whether tranexamic acid should be given to patients having an upper gastrointestinal bleed. Seven studies and two systematic reviews were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The clinical bottom line is that there is insufficient evidence, at the moment, to recommend the use of tranexamic acid in the management of upper gastrointestinal bleeding.
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Review Case Reports
BET 3: emergency management of anthracycline extravasation.
A short cut review was carried out to establish whether intravenous dexrazoxane reduces the risk of tissue necrosis after extravasation of the chemotherapy agent anthracycline. One paper directly addressed the question. The clinical bottom line is that intravenous dexrazoxane appears to be safe and may reduce the risk of tissue necrosis after extravasation of anthracycline.
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Review Case Reports
BET 2: no evidence for prophylactic antibiotics in pinna laceration.
A short cut review was carried out to establish whether prophylactic antibiotics should be given to patients with a laceration to the pinna. No studies directly answered the question. The clinical bottom line is that there is a lack of evidence on this subject and that local expert advice should be sought.