Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
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Multicenter Study
Lymph node status predicts the benefit of adjuvant chemoradiotherapy for patients with resected pancreatic cancer.
The role of adjuvant chemoradiotherapy in pancreatic cancer remains limited. The primary aim of this study was to determine the prediction of lymph node (LN) status to the benefit of adjuvant chemoradiotherapy for patients with resected pancreatic adenocarcinoma. ⋯ This study suggests adjuvant chemoradiotherapy is associated with a significant improvement of survival only in patients with LN-positive disease, while the effects of chemoradiotherapy on patients with LN-negative disease may be limited. This study may add incremental knowledge of the role of lymph node status in offering treatment with adjuvant chemoradiotherapy.