Journal of the renin-angiotensin-aldosterone system : JRAAS
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J Renin Angiotensin Aldosterone Syst · Dec 2015
Meta AnalysisAssociation of ACE insertion or deletion polymorphisms with the risk of coronary restenosis after percutaneous coronary intervention: A meta-analysis.
Previous case-control studies on the relationship between the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphisms and coronary restenosis did not reach the same conclusion. In the present study, we aimed to further evaluate the relationship between the ACE gene I/D polymorphisms and coronary restenosis, after percutaneous coronary intervention (PCI). ⋯ The present study suggested that the ACE gene I/D polymorphism was associated with coronary restenosis, regardless of age and ethnicity.
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J Renin Angiotensin Aldosterone Syst · Dec 2015
Meta AnalysisSERPINE1 rs1799768 polymorphism contributes to sepsis risk and mortality.
The present meta-analysis aimed to investigate whether there is an association between SERPINE1 rs1799768 polymorphism and sepsis risk and mortality. ⋯ In conclusion, the meta-analysis suggests that there are significant associations between SERPINE1 rs1799768 polymorphism and risk of sepsis and sepsis mortality.
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J Renin Angiotensin Aldosterone Syst · Dec 2015
Meta AnalysisAngiotensin-converting enzyme I/D polymorphism and acute respiratory distress syndrome.
Some studies have assessed the association between angiotensin-converting enzyme (ACE) I/D polymorphism and acute respiratory distress syndrome (ARDS) risk. However, the results have been inconclusive and contradictory. Therefore, we performed a meta-analysis to investigate the association between ACE I/D polymorphism and ARDS risk. ⋯ This meta-analysis suggested that ACE I/D polymorphism might contribute to the susceptibility for ARDS.