Journal of the renin-angiotensin-aldosterone system : JRAAS
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J Renin Angiotensin Aldosterone Syst · Jun 2015
Meta AnalysisThe CYP11B2 -344C/T variant is associated with ischemic stroke risk: An updated meta-analysis.
The CYP11B2 gene has been suggested to play an important role in the pathogenesis of ischemic stroke. However, the results have been inconsistent. In this study, we performed a meta-analysis to clarify the association of the CYP11B2 -344C/T variant with ischemic stroke. ⋯ The present meta-analysis supported the positive association of the CYP11B2 -344C/T variant with ischemic stroke. Further large-scale studies considering gene-gene/gene-environment interactions should be conducted to investigate the association.