ANZ journal of surgery
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ANZ journal of surgery · Apr 2012
Randomized Controlled Trial Multicenter StudySafety and efficacy of extended-release bupivacaine local anaesthetic in open hernia repair: a randomized controlled trial.
Pain relief remains a major problem in hernia surgery. SABER-Bupivacaine is an investigational extended-release formulation of bupivacaine in a resorbable matrix, which may provide up to 72 h of local pain relief. ⋯ After open inguinal hernia repair, SABER-Bupivacaine administered at the surgical site was safe and provided pain relief, reduced the need for supplemental (oral and parenteral) analgesia and did not impair wound healing.