Internal medicine journal
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Internal medicine journal · Sep 2010
Multicenter Study Comparative StudyThe four horsemen: clinicopathological correlation in 407 hospital autopsies.
Few previous papers comparing clinical diagnoses with autopsy findings present sensitivities and positive predictive values for individual conditions. The aim of this study is to determine the sensitivity and positive predictive value of current clinical diagnosis both overall and for individual conditions. ⋯ There exists a large burden of clinically undiagnosed and incorrectly diagnosed disease in hospital. Pneumonia, acute myocardial infarction, bowel ischaemia and pulmonary embolism represent important and difficult diagnostic challenges.