Internal medicine journal
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Internal medicine journal · Jul 2016
Randomized Controlled Trial Multicenter StudyNew oral anticoagulants: appropriateness of prescribing in real-world setting.
The new oral anticoagulants (NOAC) have been extensively studied in the clinical trial setting; however, concerns remain about the safety of prescribing in the elderly and patients with renal impairment. ⋯ Our findings imply that there remains considerable uncertainty about appropriate prescribing and dosing of NOAC, particularly in patients with impaired renal function. We recommend judicious prescribing and regular monitoring of renal function in patients at high risk of complications from NOAC therapy.