Internal medicine journal
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Internal medicine journal · May 2022
Review Meta AnalysisFrailty and mortality associations in patients with COVID-19: A Systematic Review and Meta-analysis.
Observational data during the pandemic have demonstrated mixed associations between frailty and mortality. ⋯ This systematic review did not demonstrate an independent association between frailty status and short-term mortality in patients with COVID-19. Patients with frailty were less commonly admitted to ICU and non-frail patients were more likely to receive IMV and had higher mortality risk. This finding may be related to allocation decisions for patients with frailty amidst the pandemic.
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Internal medicine journal · May 2022
Risk Factors for Incident Kidney Disease in Older Adults: an Australian Prospective Population-Based Study.
To determine risk factors for incident chronic kidney disease (CKD) in a large population-based cohort. ⋯ This large population-based study found multiple modifiable and non-modifiable factors were independently associated with developing CKD. In the Australian setting, the risk of CKD was higher with regional residence. Differences according to socioeconomic status were predominantly explained by age, comorbidities and harmful health-related behaviours.
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Internal medicine journal · May 2022
Chest pain and palpitations in postmenopausal women with mitral valve prolapse, is there a gastroesophageal origin?
Mitral valve prolapse (MVP) is a common disease in women, causing chest pain and palpitation due to structural and functional valve abnormality, and is sometimes associated with gastro-oesophageal reflux disease (GERD). This is a challenging clinical problem in clinical practice and requires targeted diagnostic assessment to identify the underlying causes of the symptoms, because treatment needs to be tailored, according to the causes themselves, to resolve the symptoms. ⋯ GERD is relatively common in women with MVP. Moreover, women with MVP are approximately three times more likely to be affected by GERD; the two conditions are correlated in a statistically high significant way. GERD assessment needs to be included into routine follow-up strategies in women with MVP to optimise medical therapy, improvinge symptom relief for better quality of life.