Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
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Anadolu Kardiyol Derg · Dec 2007
Meta Analysis[Aspirin in cardiovascular prevention: does the approach differ by gender?].
Although aspirin is effective in the treatment of acute coronary syndrome and in the secondary prevention of cardiovascular disease among both men and women, its use in primary prevention remains controversial. The gender-specific meta-analysis demonstrates that the specific types of benefit of aspirin therapy differ between women and men in primary prevention. ⋯ In contrast, in men; aspirin therapy significantly reduced the risk of the composite of cardiovascular events predominantly by reducing the risk of myocardial infarction. The reasons for any sex-based differences in the efficacy of aspirin for primary prevention are unclear and require further exploration.
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Anadolu Kardiyol Derg · Dec 2007
Cardiovascular risk factors in obese women and their first-degree relatives.
Evidence for a connection between obesity and cardiovascular disease is derived from epidemiological studies. The aim of this study was to evaluate the cardiovascular risk factors in obese women and their first-degree relatives. ⋯ In obese women and their relatives, body mass index and waist circumferences are related with blood pressure, total cholesterol, fibrinogen and insulin resistance. If there are obese women in family, first-degree relatives have 1.8 fold increased obesity frequency. Body mass index increases together with cardiovascular risk factors. In early term, prevention of obesity may decrease developing of cardiovascular risk.
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Aspirin is the main actor in primary and secondary preventive treatments in cardiovascular diseases. However, it has several side effects including gastrointestinal toxicity (peptic ulcer formation, bleeding). ⋯ Gastrointestinal toxicity profile does not differ between conventional and enteric-coated aspirin use. In patients who have cardiovascular disease but are at high risk for gastrointestinal bleeding, eradication of Helicobacter pylori infection and concurrent proton pump inhibitor therapy may help to reduce the risk of gastrointestinal toxicity.
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Anadolu Kardiyol Derg · Dec 2007
Does cardiopulmonary bypass change serum neuron-specific enolase levels?
The effects of cardiopulmonary bypass (CPB) on serum neuron-specific enolase (NSE) levels in patients without cognitive dysfunction and neurological deficit are not yet clarified. This study was designed to see the sole effect of extracorporeal circulation on serum NSE levels in patients without any clinically observed neurological deficit. ⋯ This study demonstrated that the possible damage of CPB on central nervous system and on blood cells did not reach to the extent of causing any significant increase in serum NSE levels in non-complicated patients undergoing open-heart surgery.
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Anadolu Kardiyol Derg · Dec 2007
Serum lipid profiles including non-high density lipoprotein cholesterol levels in Turkish school-children.
Early detection of dyslipidemia and long-term prevention of atherosclerosis by controlling risk factors should begin in childhood. The purpose of this study was to evaluate the prevalence of dyslipidemia according to non-high density lipoprotein cholesterol (non-HDL-C) levels in children and also evaluate serum non-HDL-C levels according to age groups, gender difference and living areas. ⋯ Our results are indicative of the prevalence of dyslipidemia in children is considerably common in our population. Serum non-HDL-C levels could be used as an appropriate tool for detecting dyslipidemia in childhood.