Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
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Anadolu Kardiyol Derg · May 2011
Randomized Controlled TrialComparison of the effects of sevoflurane and isoflurane on myocardial protection in coronary bypass surgery.
The aim of this prospective randomized study was to compare the myocardial protective effects of sevoflurane and isoflurane during coronary bypass surgery. ⋯ Sevoflurane provides a better myocardial protection than isoflurane, as may be inferred by the lower levels of the myocardial injury markers troponin-T and CK-MB observed with sevoflurane.
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Anadolu Kardiyol Derg · Dec 2009
Randomized Controlled TrialFurosemide infusion prevents the requirement of renal replacement therapy after cardiac surgery.
Acute kidney injury (AKI) is a devastating complication following cardiac surgery and the ideal management is controversial. This prospective, randomized, open-label and double-blinded study analyzed the renoprotective effects of furosemide infusion and intermittent bolus therapy administered with dopamine infusion in cardiac surgical patients. ⋯ Acute kidney injury necessitating RRT makes a small percentage of patients undergoing cardiac surgery and if RRT is not required the survival is excellent. Continuous infusion of furosemide seems to be effective in promoting diuresis and decreasing the need for RRT. However further multicenter studies with different doses of furosemide are required to confirm these results.
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Anadolu Kardiyol Derg · Oct 2009
Randomized Controlled TrialEfficacy of gabapentin versus diclofenac in the treatment of chest pain and paresthesia in patients with sternotomy.
Chronic post-sternotomy chest pain and paresthesia (PCPP) are frequently seen and reduce the quality of life. We aimed to demonstrate the efficacy and safety of gabapentin compared with diclofenac in the treatment of PCPP and to elucidate the similarities of PCPP to neuropathic pain syndromes. ⋯ Both gabapentin and diclofenac are effective in the treatment of chronic PCPP, without obvious side effects. However, gabapentin is found to be superior to diclofenac and its effects sustain longer. The results show that there may be some evidence in PCPP as a kind of neuropathic pain.
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Anadolu Kardiyol Derg · Aug 2009
Randomized Controlled TrialThe effects of intra-operative amiodarone loading on the systemic inflammatory response syndrome induced by cardiopulmonary bypass.
Cardiopulmonary bypass (CPB) leads to systemic inflammatory response syndrome (SIRS). In vitro studies showed that amiodarone blocked cytokine production. The aim of this study was to evaluate the effect of intra-operative amiodarone loading on SIRS. ⋯ The results indicate that intraoperative loading of amiodarone, which is used for atrial fibrillation prophylaxis, does not seem to alter inflammatory response during CPB.
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Anadolu Kardiyol Derg · Feb 2009
Randomized Controlled Trial Comparative StudyEpidural anesthesia versus general anesthesia in patients undergoing minimally invasive direct coronary artery bypass surgery.
Minimally invasive direct coronary artery bypass (MIDCAB) surgery in the awake patient with epidural anesthesia had been previously reported. However, there is no prospective randomized study comparing MIDCAB surgery with epidural anesthesia versus general anesthesia. ⋯ It can be concluded that, similar surgical results can be achieved by MIDCAB surgery with general or epidural anesthesia. Although epidural anesthesia has no impact on the degree of patient satisfaction after the procedure, it yields significantly shorter ICU and hospital stay periods, which may result in more efficient use of hospital resources.