Expert review of molecular diagnostics
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Expert Rev. Mol. Diagn. · Jun 2015
ReviewRecent advances of microRNA-based molecular diagnostics to reduce false-positive lung cancer imaging.
Lung cancer is the leading cause of cancer deaths in the world. Advances in early detection crucial to enable timely curative surgery have been made in recent years. ⋯ MicroRNA are a new class of blood-based biomarkers useful for early lung cancer detection and prognosis definition. Here, we discuss the seminal publications that reported circulating microRNA signatures with the greatest potential to impact clinical activity and patient care.