Revista de saúde pública
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Revista de saúde pública · Jan 2020
Cross-cultural adaptation and content validity of leisure attitude measurement for older adults.
To adapt the Leisure Attitude Measurement to the Brazilian culture and to evaluate the face and content validity of the Brazilian version for older population. ⋯ The instrument's adaptation to the Brazilian culture was successful and allows to assess the attitude of the elderly in relation to leisure in a reliable manner, even though the results are a preliminary version, to be concluded after the psychometric analysis. The instrument could be incorporated in various health fields in Brazil and will allow the production of standardized data, comparison between cultures and strategies to promote positive attitudes towards leisure.
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Revista de saúde pública · Jan 2020
Primum non nocere - Are chloroquine and hydroxychloroquine safe prophylactic/treatment options for SARS-CoV-2 (covid-19)?
Chloroquine (CQ) and its analog hydroxychloroquine (HCQ) were recently included in several clinical trials as potential prophylactic and therapeutic options for SARS-COV-2 infection/covid-19. However, drug effectiveness in preventing, treating, or slowing the progression of the disease is still unknown. ⋯ On the other hand, while the potential effectiveness of CQ/HCQ is, at best, hypothetical, their side effects are factual and most worrisome, particularly when considering vulnerable groups of patients being treated with these drugs. in this comment, we briefly explain the possible mechanisms of action of CQ/HCQ for treating other diseases, possible actions against covid-19, and their potent side effects, in order to reinforce the necessity of evaluating the benefit-risk balance when widely prescribing these drugs for SARS-COV-2 infection/covid-19. We conclude by strongly recommending against their indiscriminate use.