Pain practice : the official journal of World Institute of Pain
-
Review Meta Analysis
Semi-invasive therapies for pain in knee osteoarthritis: A systematic review and network meta-analysis.
The increasing number of semi-invasive pain therapies in knee osteoarthritis poses challenges in decision-making. This review aimed to simultaneously compare established intra-articular therapies with newer peri-articular therapies and explore effect modifiers. ⋯ Although there is robust evidence suggesting greater efficacy of PRP, potentially including biologics, over other interventions, future research is needed to identify the phenotype or patient subgroup that would benefit most from PRP.