Latest Articles
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Meta Analysis
Mammographic screening trials for women aged under 50. A quality assessment and meta-analysis.
To carry out a systematic quality review and meta-analysis of all randomised trials of mammographic screening that included women aged under 50 years. ⋯ These analyses suggest little, if any, benefit for women under 50 years of age. The results are not explained by the quality of the trials or the radiology. We recommend that women in this age group intending to be screened should be fully informed of these results.
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Meta Analysis
The incidence of aspiration associated with the laryngeal mask airway: a meta-analysis of published literature.
To determine the incidence of pulmonary aspiration with the laryngeal mask airway (LMA). ⋯ The evidence to date suggests that the pulmonary aspiration with the LMA is uncommon and comparable to that for outpatient anesthesia with the face mask and tracheal tube. Meticulous attention to selection of low-risk patients and appropriate operative procedures and avoidance of light anesthesia should reduce the incidence even further.
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To evaluate diabetes mellitus as a risk factor for pancreatic cancer with the consideration that diabetes may also be a consequence of pancreatic cancer. ⋯ Pancreatic cancer occurs with increased frequency among persons with long-standing diabetes.
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Meta Analysis
Effect of out-of-hospital defibrillation by basic life support providers on cardiac arrest mortality: a metaanalysis.
Although some studies demonstrate otherwise, we hypothesized that metaanalysis would demonstrate a reduction in the relative risk of mortality when basic life support (BLS) providers can defibrillate out-of-hospital cardiac arrest patients. ⋯ BLS defibrillation can reduce the relative risk of death for out-of-hospital cardiac arrest victims in ventricular fibrillation. Weaknesses in individual study designs and regional clustering limit the strength of this metaanalysis and conclusion.
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J Expo Anal Environ Epidemiol · Apr 1995
Meta AnalysisA meta-analytical approach examining the potential relationship between talc exposure and ovarian cancer.
The concern that use of talc or talc-containing substances in the perineal region of women may subject them to an increased risk for ovarian cancer has become an important issue in the study of ovarian cancer. The purpose of this paper is to examine whether this concern, heightened by several epidemiological studies purporting to show an increased risk, is valid. Epidemiological studies examining the possibility of this relationship are reviewed, and meta-analyses of their results are performed. The conclusion reached herein is that the evidence regarding the risk of ovarian cancer associated with talc exposure is equivocal, and further examination of the relationship is required before a sound conclusion can be made.