Articles: disease.
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Seventy-nine patients with endometrial carcinoma were compared with 203 control subjects regarding their use of combination-product oral contraceptives (OCs). Overall, 6.3% of patients and 15.3% of control subjects had used these products. The risk of endometrial cancer for users of OCs was less than half the risk for nonusers. ⋯ Recent users were strongly protected, whereas discontinuation resulted in risks returning to those of nonusers. Furthermore, OCs with predominantly progestational effects of intermediate formulations produced greater protection than those with predominantly estrogens. This pattern of results is biologically consistent with a protective effect of combination-product OCs against endometrial carcinoma.
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Because a line was inadvertently omitted, the article "Reagan reforms create upheaval at NIOSH" (News and Comment, 9 Oct., p. 166) stated on p. 168 that Donald Millar, new director of the National Institute for Occupational Safety and Health (NIOSH), believes that NIOSH should be separated from the Centers for Disease Control in Atlanta. The sentence should have read, "Millar says one of the things he learned as acting director [of NIOSH] is that NIOSH should be moved to Atlanta or that its ties to CDC should be severed." Millar, who wants strengthened ties between NIOSH and CDC, favors the former alternative.