Articles: disease.
-
Pol. Arch. Med. Wewn. · Jan 2024
The treatment regimens and disease activity could alter the salivary myeloperoxidase levels in patients with inflammatory bowel diseases.
Inflammatory bowel diseases (IBDs) present with alternating periods of exacerbation and remission; therefore, it is necessary to develop noninvasive diagnostic tools to control the disease activity and improve therapeutic effectiveness. Recently, we have found that patients with ulcerative colitis (UC) who qualified for biologic therapy had significantly lower salivary myeloperoxidase (MPO) levels. ⋯ Salivary MPO levels changed depending on the disease activity in the patients with UC. Decreased MPO concentration in the saliva could be a predictor of clinically active UC.
-
Cutaneous larva migrans can affect even athletes who travelled to play beach volleyball in Zanzibar. We describe a cluster of CLM infections in travellers who contracted the disease during their trip to Africa, rather than bringing a volleyball trophy. Despite presenting typical changes, all of them were misdiagnosed.
-
Randomized Controlled Trial
Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial.
Excess aldosterone accelerates chronic kidney disease progression. This phase 2 clinical trial assessed BI 690517, an aldosterone synthase inhibitor, for efficacy, safety, and dose selection. ⋯ Boehringer Ingelheim.