Articles: disease.
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At present, nucleic acid testing is the gold standard for diagnosing influenza A, however, this method is expensive, time-consuming, and unsuitable for promotion and use in grassroots hospitals. This study aimed to establish a diagnostic model that could accurately, quickly, and simply distinguish between influenza A and influenza like diseases. ⋯ A computer algorithm diagnosis model of influenza A in children based on blood routine test data was established, which could identify children with influenza A more accurately in the early stage, and was easy to popularize.
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By conducting an in-depth investigation and analysis of the health human resource framework within the Urumqi Center for Disease Control and Prevention (CDC), this study aims to offer valuable insights for the objective assessment and future enhancement of its talent development endeavors. A questionnaire survey was administered, followed by a descriptive analysis, involving the healthcare professionals affiliated with the Urumqi Center for CDC. The Urumqi Center for CDC exhibited a lower compilation number than its on-duty personnel count. ⋯ The human resource count in both Urumqi's city and county (district) level CDCs has decreased, but the relative numbers have improved, indicating enhanced quality and a younger workforce. The municipal-level CDC boasts a superior human resource structure compared to the county (district) level, with better fairness in population distribution by area than geography. Allocation equity within the central urban area is higher than in distant urban areas, highlighting regional disparities as a significant factor.
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Lillegraven S, Paulshus Sundlisaeter N, Aga AB, et al. Effect of tapered versus stable treatment with tumour necrosis factor inhibitors on disease flares in patients with rheumatoid arthritis in remission: a randomised, open label, non-inferiority trial. Ann Rheum Dis. 2023;82:1394-1403. 37607809.
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First-line treatment of diffuse large B-cell lymphoma (DLBCL) achieves durable remission in approximately 60% of patients. In relapsed or refractory disease, only about 20% achieve durable remission with salvage chemoimmunotherapy and consolidative autologous stem cell transplantation (ASCT). The ZUMA-7 (axicabtagene ciloleucel [axi-cel]) and TRANSFORM (lisocabtagene maraleucel [liso-cel]) trials demonstrated superior event-free survival (and, in ZUMA-7, overall survival) in primary-refractory or early-relapsed (high-risk) DLBCL with chimeric antigen receptor T-cell therapy (CAR-T) compared with salvage chemoimmunotherapy and consolidative ASCT; however, list prices for CAR-T exceed $400 000 per infusion. ⋯ No research-specific funding.
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Acute phlegmonous esophagitis (APE) is bacterial infection of the submucosal and muscularis layers of the esophagus. APE is a rare but life-threatening disease, and few studies have reported it. ⋯ As APE is rare but deadly, strategies to identify APE in patients with chest pain or dysphagia are needed in emergency department.