Articles: disease.
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Br J Obstet Gynaecol · Sep 1998
Randomized Controlled Trial Clinical TrialA randomised placebo controlled trial of oral misoprostol in the third stage of labour.
To compare oral misoprostol 400 microg with placebo in the routine management of the third stage of labour. ⋯ Shivering has been shown in this study to be a specific side effect of misoprostol administered orally in the puerperium. No serious side effects were noted. Misoprostol shows promise as a method of preventing postpartum haemorrhage. Because of the potential benefits for childbearing women, particularly those in developing countries, further research to determine its effects with greater certainty should be expedited.
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Randomized Controlled Trial Clinical Trial
A controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseases.
Nonoxynol 9 is a proved spermicide, but whether it is also a microbicide is uncertain. A truly effective vaginal microbicide would reduce the susceptibility of women to sexually transmitted diseases, including infection with the human immunodeficiency virus (HIV). ⋯ The use of a nonoxynol 9 vaginal film did not reduce the rate of new HIV, gonorrhea, or chlamydia infection in this group of sex workers who used condoms and received treatment for sexually transmitted diseases.
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Randomized Controlled Trial Clinical Trial
A randomized, community trial of intensive sexually transmitted disease control for AIDS prevention, Rakai, Uganda.
To describe the design and first-round survey results of a trial of intensive sexually transmitted disease (STD) control to reduce HIV-1 incidence. ⋯ Testing the effects of STD control on AIDS prevention is feasible in this Ugandan setting.
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Randomized Controlled Trial Clinical Trial
Randomised trial of effects of vitamin supplements on pregnancy outcomes and T cell counts in HIV-1-infected women in Tanzania.
In HIV-1-infected women, poor micronutrient status has been associated with faster progression of HIV-1 disease and adverse birth outcomes. We assessed the effects of vitamin A and multivitamins on birth outcomes in such women. ⋯ Multivitamin supplementation is a low-cost way of substantially decreasing adverse pregnancy outcomes and increasing T-cell counts in HIV-1-infected women. The clinical relevance of our findings for vertical transmission and clinical progression of HIV-1 disease is yet to be ascertained.
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The Journal of nutrition · May 1998
Randomized Controlled Trial Comparative Study Clinical TrialIron nutritional status is improved in Brazilian preterm infants fed food cooked in iron pots.
To determine the efficacy of cooking food in iron pots to prevent anemia in premature infants, a longitudinal study on iron nutritional status was conducted in preterm, healthy infants from families of low socioeconomic level between mo 4 and 12 of life. The infants were divided randomly into two groups. The study group consisted of 22 infants whose food was cooked in iron pots; the control group consisted of 23 infants whose food was cooked in aluminum pots. ⋯ Iron deficiency anemia (hemoglobin