Articles: patients.
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Multicenter Study
The Reliability and Validity of the Thoracolumbar Injury Classification System in Pediatric Spine Trauma.
The thoracolumbar injury classification system (TLICS) was evaluated in 20 consecutive pediatric spine trauma cases. ⋯ 4.
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Multicenter Study Comparative Study Observational Study
Early mobilisation in intensive care units in Australia and Scotland: a prospective, observational cohort study examining mobilisation practises and barriers.
Mobilisation of patients in the intensive care unit (ICU) is an area of growing research. Currently, there is little data on baseline mobilisation practises and the barriers to them for patients of all admission diagnoses. ⋯ This is the first study to benchmark baseline practise of early mobilisation internationally, and it demonstrates variation in early mobilisation practises between Australia and Scotland.
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Bmc Health Serv Res · Sep 2015
Multicenter StudyAssociation Between Nighttime Discharge from the Intensive Care Unit and Hospital Mortality: A Multi-Center Retrospective Cohort Study.
We aimed to determine the impact of nighttime discharge from the intensive care unit (ICU) to the ward on hospital mortality and readmission rates in consecutive critically ill patients admitted to five Canadian ICUs. We hypothesized that hospital mortality and readmission rates would be higher for patients discharged after hours compared with discharge during the day. ⋯ In a large integrated health region, 1 in 5 ICU patients are discharged at nighttime, a factor with increasing occurrence during our study and shown to be independently associated with higher hospital mortality.
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Randomized Controlled Trial Multicenter Study
Induction chemoradiation in stage IIIA/N2 non-small-cell lung cancer: a phase 3 randomised trial.
One of the standard options in the treatment of stage IIIA/N2 non-small-cell lung cancer is neoadjuvant chemotherapy and surgery. We did a randomised trial to investigate whether the addition of neoadjuvant radiotherapy improves outcomes. ⋯ Swiss State Secretariat for Education, Research and Innovation (SERI), Swiss Cancer League, and Sanofi.
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Multicenter Study
The effect of early, comprehensive genomic testing on clinical care in neonatal diabetes: an international cohort study.
Traditional genetic testing focusses on analysis of one or a few genes according to clinical features; this approach is changing as improved sequencing methods enable simultaneous analysis of several genes. Neonatal diabetes is the presenting feature of many discrete clinical phenotypes defined by different genetic causes. Genetic subtype defines treatment, with improved glycaemic control on sulfonylurea treatment for most patients with potassium channel mutations. We investigated the effect of early, comprehensive testing of all known genetic causes of neonatal diabetes. ⋯ Wellcome Trust and Diabetes UK.