Articles: child.
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Pediatr Crit Care Me · Aug 2016
Multicenter Study Observational StudyBurden and Outcomes of Severe Pertussis Infection in Critically Ill Infants.
Despite World Health Organization endorsed immunization schedules, Bordetella pertussis continues to cause severe infections, predominantly in infants. There is a lack of data on the frequency and outcome of severe pertussis infections in infants requiring ICU admission. We aimed to describe admission rates, severity, mortality, and costs of pertussis infections in critically ill infants. ⋯ Pertussis continues to cause significant morbidity and mortality in infants, in particular during the first months of life. Improved strategies are required to reduce the significant healthcare costs and disease burden of this vaccine-preventable disease.
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J. Neurol. Neurosurg. Psychiatr. · Aug 2016
Multicenter StudyAntibodies to MOG and AQP4 in children with neuromyelitis optica and limited forms of the disease.
To determine the frequency and clinical-radiological associations of antibodies to myelin oligodendrocyte glycoprotein (MOG) and aquaporin-4 (AQP4) in children presenting with neuromyelitis optica (NMO) and limited forms. ⋯ 67% of all children presenting with NMO or limited forms tested positive for MOG- or AQP4-antibodies. MOG-antibody positivity was associated with distinct features. We therefore recommend to measure both antibodies in children with demyelinating syndromes.
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Multicenter Study Observational Study
Risk factors and outcomes of in-hospital cardiac arrest following pediatric heart operations of varying complexity.
Multi center data regarding cardiac arrest in children undergoing heart operations of varying complexity are limited. ⋯ This study suggests that the patients undergoing high complexity operations are a higher risk group with increased prevalence of post-operative cardiac arrest. These data further suggest that patients undergoing high complexity operations can be rescued after cardiac arrest with a high survival rate.
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Pediatr Crit Care Me · Aug 2016
Multicenter Study Observational StudyEpidemiology of Sepsis in Children Admitted to PICUs in South America.
To report the prevalence of sepsis within the first 24 hours at admission and the PICU sepsis-related mortality among critically ill children admitted to PICU in South America. ⋯ We observed high prevalence of sepsis and sepsis-related mortality among this sample of children admitted to PICU in South America. Mortality was associated with greater severity of illness at admission and potentially associated with late PICU referral.
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J Neurosurg Pediatr · Aug 2016
Multicenter StudyMulticenter retrospective evaluation of the validity of the Thoracolumbar Injury Classification and Severity Score system in children.
OBJECTIVE The Thoracolumbar Injury Classification and Severity Score (TLICS) system was developed to streamline injury assessment and guide surgical decision making. To the best of the authors' knowledge, external validation in the pediatric age group has not been undertaken prior to this report. METHODS This study evaluated the use of the TLICS in a large retrospective series of children and adolescents treated at 4 pediatric medical centers (Texas Children's Hospital, Children's Healthcare of Atlanta, Riley Children's Hospital, and Doernbecher Children's Hospital). ⋯ In the surgical group, TLICS recommendations matched treatment in 93% of cases. The TLICS recommendations and surgeon decision making displayed very good concordance. The TLICS appears to be effective in the classification of thoracic and lumbar spine injuries and in guiding treatment in the pediatric age group.