Articles: general-anesthesia.
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Randomized Controlled Trial Multicenter Study Clinical Trial
A randomized, double-blind pilot study examining the use of intravenous ondansetron in the prevention of postoperative nausea and vomiting in female inpatients.
To compare the efficacy and safety profiles of intravenous (IV) ondansetron (two 8 mg doses 8 hours apart) and a placebo when used in the prevention of postoperative nausea and emesis (vomiting or retching). ⋯ Prophylactic IV ondansetron appears to be safe and causes a significant reduction in the frequency and severity of postoperative nausea and emesis.
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In 1988, a confidential postal questionnaire was prepared in order to assess the techniques used routinely in France for prophylaxis of aspiration of gastric contents in obstetrics. Of the 297 anaesthetists who responded, 81% (237) worked almost always and 19% worked occasionally in obstetric anaesthesia. Although obstetric anaesthesia is considered to carry a particular risk of aspiration of gastric contents (88.5% of responders), only 23% used in every case a complete set of prophylactic measures. ⋯ Among the users of cricoid pressure, 52% were able to describe precisely the technique. Tracheal intubation is considered mandatory when general anaesthesia is performed for Caesarean section but not for uterine revision or instrumental manoeuvre. 74% of obstetric anaesthetists believe that regional anaesthesia is the best anaesthetic technique for Caesarean section. This survey has shown both positive results indicating that continuing medical education of French anaesthetists follows at least in part the 'state of the art' and insufficiencies indicating that training continues to be necessary to reduce the mortality related to aspiration of gastric contents.
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Randomized Controlled Trial Multicenter Study Clinical Trial
A double-blind, placebo-controlled pilot study examining the effectiveness of intravenous ondansetron in the prevention of postoperative nausea and emesis.
To compare the efficacy and safety profiles of ondansetron and a placebo when infused immediately prior to anesthesia induction for the prevention of postoperative nausea and emesis (vomiting or retching). ⋯ Ondansetron, infused IV before anesthesia induction, appears to be safe and effective when used in the prevention of postoperative nausea and emesis.
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Arthroscopic shoulder surgery can be performed under regional or general anesthesia. The objective of this study was to demonstrate that regional anesthesia has several benefits over general anesthesia for this type of surgery, particularly in the ambulatory patient. ⋯ It provided excellent intraoperative analgesia and muscle relaxation. Postoperatively, regional anesthesia resulted in fewer side effects, fewer hospital admissions, and a shorter hospital stay than did general anesthesia.
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Anesthesia progress · Jan 1993
Comparative Study Clinical Trial Controlled Clinical TrialCerebral arterial blood flow velocity during induction of general anesthesia: rapid intravenous induction versus awake intubation.
Changes in middle cerebral arterial flow velocity (MCAV) during rapid intravenous induction and awake intubation using transcranial Doppler sonography were investigated. The study involved 20 patients without disorders of the central nervous or cardiovascular systems who were scheduled for maxillofacial surgery. In the intravenous induction group, anesthesia was induced with sodium thiopental, and orotracheal or nasotracheal intubation was facilitated with succinylcholine chloride or alcuronium chloride. ⋯ During awake intubation, blood pressures were increased by endotracheal intubation. MCAV was decreased from the administration of diazepam to the transtracheal injection of lidocaine, but returned to the control value from endotracheal spray to endotracheal intubation. These results suggest that smooth awake intubation may be the safest method of induction for patients with cerebrovascular disorders.