Articles: cancer.
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Randomized Controlled Trial Multicenter Study
Effects of yoga on cancer-related fatigue and global side-effect burden in older cancer survivors.
Sixty percent of cancer survivors are 65years of age or older. Cancer and its treatments lead to cancer-related fatigue and many other side effects, in turn, creating substantial global side-effect burden (total burden from all side effects) which, ultimately, compromises functional independence and quality of life. Various modes of exercise, such as yoga, reduce cancer-related fatigue and global side-effect burden in younger cancer survivors, but no studies have specifically examined the effects of yoga on older cancer survivors. ⋯ YOCAS©® is an effective standardized yoga intervention for reducing cancer-related fatigue, physical fatigue, mental fatigue, and global side-effect burden among older cancer survivors.
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Anticancer research · Dec 2014
Randomized Controlled TrialMelatonin in patients with cancer receiving chemotherapy: a randomized, double-blind, placebo-controlled trial.
The MIRCIT trial was a randomized, double-blind, placebo-controlled study of advanced Non-small cell lung cancer (NSCLC). ⋯ Melatonin in combination with chemotherapy did not affect survival and adverse events of advanced patients with NSCLC, but there was a trend for better HRQoL.
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J Pain Symptom Manage · Dec 2014
Randomized Controlled TrialPalliative radiation before hospice: the long and the short of it.
Randomized data support shorter radiotherapy courses for management of cancer-related symptoms in the palliative setting. ⋯ This study found relatively long courses of radiotherapy before short lengths of survival on hospice. Future research is needed to identify barriers to shorter radiotherapy courses.
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Gen Hosp Psychiatry · Nov 2014
Randomized Controlled TrialCost effectiveness of telecare management for pain and depression in patients with cancer: results from a randomized trial.
Pain and depression are prevalent and treatable symptoms among patients with cancer, yet they are often undetected and undertreated. The Indiana Cancer Pain and Depression (INCPAD) trial demonstrated that telecare management can improve pain and depression outcomes. This article investigates the incremental cost effectiveness of the INCPAD intervention. ⋯ Centralized telecare management, coupled with automated symptom monitoring, appears to be a cost effective intervention for managing pain and depression in cancer patients.
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J Pain Symptom Manage · Nov 2014
Randomized Controlled TrialA randomized trial of the effectiveness of topical "ABH Gel" (Ativan(®), Benadryl(®), Haldol(®)) vs. placebo in cancer patients with nausea.
The topical gel known as "ABH gel," comprising lorazepam (Ativan(®)), diphenhydramine (Benadryl(®)), and haloperidol (Haldol(®)), is frequently used to treat nausea because of its perceived efficacy, relatively low cost, and ease of use in the home setting. There are limited scientific data on this medication, however. Recent pilot studies showed no absorption of the active ingredients of the gel, prompting further prospective studies into the cause of the perceived efficacy in the clinical setting. ⋯ ABH gel in its current formulation should not be used in cancer patients experiencing nausea.