Articles: intubation.
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Randomized Controlled Trial Clinical Trial
Topical analgesia of the upper airway with lignocaine. Absorption and its relationship to toxic and anti-arrhythmic levels.
After routine topical application of lignocaine to the upper airway before passage of an endotracheal tube during general anaesthesia, plasma lignocaine levels were assayed in 20 artificially ventilated and 21 spontaneously ventilating patients. Systemic absorption was found to be rapid but very variable. Mean peak level were attained 15 minutes before spraying and were well below the convulsive threshold for anaesthetized patients, while reputedly anti-arrhythmic levels were achieved by 5 minutes and maintained until 40 minutes. Levels in the ventilated group were significantly higher 20 minutes after administration.
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Comparative Study Clinical Trial Controlled Clinical Trial
Sore throat after operation: influence of tracheal intubation, intracuff pressure and type of cuff.
One hundred and eighty-four patients were studied to elucidate the contribution of intracuff pressure and cuff type to the occurrence of sore throat and hoarseness after operation. The patients were allocated to one of the following groups: A = mask only; B = reusable Rüsch tube with intermittent cuff volume adjustment; C = reusable Rüsch tube without cuff volume adjustment; D = disposable Portex Blue Line tube with intermittent cuff volume adjustment; E = disposable Shiley Low Pressure tube with intermittent cuff volume adjustment. Nitrous oxide was a component of anaesthesia in all patients. ⋯ All sequelae occurred less frequently in group A than in any of the other groups (P less than 0.025). Women were more likely to develop sore throat after intubation than were men (P less than 0.01). A possible relationship between differences in cuff-trachea contact area is postulated.