Articles: treatment.
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Meta Analysis
Meta-analysis of risk factors for cardiovascular disease in patients with rheumatoid arthritis.
Cardiovascular disease (CVD) is a common complication of rheumatoid arthritis (RA). We aimed to explore the risk factors for cardiovascular disease in patients with rheumatoid arthritis and provide a scientific basis on effective prevention and treatments for CVD in RA patients. ⋯ C-reactive protein, TC, hypertension, and D dimer are the main risk factors for CVD in patients with RA. No protective factors were found.
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Meta Analysis
Prognostic value of pretreatment modified Glasgow Prognostic Score in small cell lung cancer: A meta-analysis.
The prognostic role of pretreatment modified Glasgow Prognostic Score (mGPS) in small cell lung cancer (SCLC) patients remains unclear now. ⋯ Pretreatment mGPS was significantly associated with prognosis in SCLC and patients with elevated mGPS experienced obviously worse survival. Thus, pretreatment mGPS could serve as a novel and reliable prognostic indicator in SCLC patients.
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Meta Analysis
Efficacy and safety of agomelatine in the treatment of patients with depressive disorder: A meta-analysis.
To systematically assess the efficacy and safety of agomelatine in the treatment of patients with depressive disorder. ⋯ Agomelatine was superior comparable to placebo in the treatment of patients with depressive disorder, and has fewer adverse events.
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Meta Analysis
Minocycline in depression not responding to first-line therapy: A systematic review and meta-analysis.
Major depressive disorder is often resistant to first-line treatment, with around 30% failing to respond to traditional therapy. Treatment-resistant depression results in prolonged hospitalization and healthcare costs. Anti-inflammatory drugs have shown promising results in depression not responding to initial therapy. Minocycline has anti-inflammatory properties and crosses the blood-brain barrier. It has demonstrated varied results in several randomized controlled trials (RCTs). ⋯ CRD42023398476 (PROSPERO).
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Review Meta Analysis
The prognostic impact of pre-treatment cachexia in resectional surgery for oesophagogastric cancer: a meta-analysis and meta-regression.
Cancer cachexia is not purely an end-stage phenomenon and can influence the outcomes of patients with potentially curable disease. This review examines the effect of pre-treatment cachexia on overall survival, in patients undergoing surgical resection of oesophagogastric cancer. ⋯ Pre-treatment cachexia adversely influences overall survival following resection of an oesophagogastric malignancy.