Articles: coronavirus.
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Mayo Clinic proceedings · Jun 2021
ReviewLeveraging the Electronic Health Record to Address the COVID-19 Pandemic.
The coronavirus disease 2019 (COVID-19) pandemic continues its global spread. Coordinated effort on a vast scale is required to halt its progression and to save lives. Electronic health record (EHR) data are a valuable resource to mitigate the COVID-19 pandemic. ⋯ When linked to "omics" data, the EHR could facilitate identification of genetic susceptibility variants, leading to insights into risk factors, disease complications, and drug repurposing. Real-time monitoring of patients could enable early detection of potential complications, informing appropriate interventions and therapy. We reviewed relevant articles from PubMed, MEDLINE, and Google Scholar searches as well as preprint servers, given the rapidly evolving understanding of the COVID-19 pandemic.
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Coronavirus disease 2019 can cause significant mortality in the elderly in long-term care facilities (LTCF). We describe 4 LTCF outbreaks where mass testing identified a high proportion of asymptomatic infections (4%-41% in healthcare workers and 20%-75% in residents), indicating that symptom-based screening alone is insufficient for monitoring for COVID-19 transmission.
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Palliative medicine · Jun 2021
Pharmacological strategies used to manage symptoms of patients dying of COVID-19: A rapid systematic review.
COVID-19 has tragically resulted in over 2.5 million deaths globally. Despite this, there is a lack of research on how to care for patients dying of COVID-19, specifically pharmacological management of symptoms. ⋯ A higher proportion of patients required continuous subcutaneous infusion than is typically encountered in palliative care. Doses of medications required to manage symptoms were generally modest. There was no evidence of a standardised yet holistic approach to measure effectiveness of these medications and this needs to be urgently addressed.
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Observational Study
Hyper-Inflammatory Response Involves in Cardiac Injury among Patients with Coronavirus Disease 2019.
Inflammation can facilitate development of coronavirus disease 2019 (COVID-19) and cardiac injury is associated with worse clinical outcomes. However, data are relatively scarce on the association between hyper-inflammatory response and cardiac injury among COVID-19 patients. ⋯ Cardiac injury was associated with elevated levels of inflammatory cytokines among severe and critically ill patients with COVID-19, suggesting that hyper-inflammatory response may involve in cardiac injury.
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Diseases caused by the novel coronavirus (SARS-CoV-2) have led to a pandemic in a very dynamic manner. The epidemiological situation of national importance required infection control measures with the aim of reducing morbidity and mortality. An overburdening of the healthcare system should be avoided. The measures taken to combat the pandemic have had an impact on public and private life. Patients suffering from chronic pain have also been greatly affected. ⋯ It is necessary to maintain the limited but still existing options of coordinated care for pain patients following a multimodal inpatient stay, even in difficult situations. The negative effects of a reduction in medical care are an argument in favor of multimodal outpatient care, especially after inpatient treatment.