Articles: sepsis.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Feb 2020
Multicenter Study Observational Study[Diagnostic value of the Sepsis-3 standard for patients with sepsis: a multi-center prospective, observational clinical study].
To explore the value of Sepsis-3 standard in diagnosis of patients with sepsis. ⋯ The Sepsis-3 standard is superior to the Sepsis-1 standard in the diagnosis and prediction of 28-day mortality in patients with sepsis. qSOFA can be used as an early tool for rapid screening of patients with high-risk sepsis in the ICU bedside.
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Critical care medicine · Jan 2020
Multicenter Study Observational StudyBioactive Adrenomedullin, Organ Support Therapies, and Survival in the Critically Ill: Results from the French and European Outcome Registry in ICU Study.
Adrenomedullin has vascular properties and elevated plasma adrenomedullin levels were detected in sepsis. We assessed, in septic and nonseptic ICU patients, the relation between circulating adrenomedullin, the need for organ support and mortality, using an assay of bioactive adrenomedullin. ⋯ Early measurement of bioactive adrenomedullin is a strong predictor of the need of organ support and of short-term mortality in critically ill patients.
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Multicenter Study Observational Study
Early diagnosis of sepsis in emergency departments, time to treatment, and association with mortality: An observational study.
Early recognition of sepsis is critical for timely initiation of treatment. The first objective of this study was to assess the timeliness of diagnostic procedures for recognizing sepsis in emergency departments. We define diagnostic procedures as tests used to help diagnose the condition of patients. The second objective was to estimate associations between diagnostic procedures and time to antibiotic treatment, and to estimate associations between time to antibiotic treatment and mortality. ⋯ Key procedures for recognizing sepsis were delayed or not completed in a substantial proportion of patients admitted to the emergency department with sepsis. Delay or non-completion of key diagnostic procedures was associated with prolonged time to treatment with antibiotics. This suggests a need for systematic improvement in the initial management of patients admitted to emergency departments with sepsis.
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Randomized Controlled Trial Multicenter Study Comparative Study
Effects of oxygen on post-surgical infections during an individualised perioperative open-lung ventilatory strategy: a randomised controlled trial.
In the context of optimal, individualised lung ventilation, high inspired oxygen does not reduce surgical infections compared with conventional FiO2.
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Multicenter Study
Sepsis and septic shock in emergency departments of Mexico: a multicenter point prevalence study.
Sepsis is one of the main reasons for consultation at emergency departments. ⋯ Se encontró alta prevalencia de la sepsis en los servicios de urgencias médicas mexicanos. La mortalidad de los pacientes con choque séptico fue similar e, incluso, mayor a la reportada internacionalmente.