Articles: chronic.
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Pulmonary and Sleep MedicineSESSION TYPE: Slide PresentationPRESENTED ON: Saturday, March 22, 2014 at 09:00 AM - 10:00 AMPURPOSE: Intermittent hypoxia and increase sympathetic activity during apnea episodes may cause systemic inflammation via down-regulation of regulatory T-cell (Treg cells). This may contribute to premature atherosclerosis leading to an increase in the size of arterial intima-media thickness (IMT). To evaluate the relationship between Treg plasma cells and intima-media thickness (IMT) in non-OSA and OSA patients without comorbidities ⋯ The effect of nocturnal intermittent hypoxia and increase sympathetic activity is not homogeneous among all patients with OSA. It seems that a subset of patients exhibit an increased risk of subclinical atherosclerosis associated with a down-regulation of regulatory T-cells. This subgroup of patients probably represents a particular phenotypic presentation of OSA that merits a specific treatment. Supported by ISCIII grant PI12/02175 and SEPAR-2014DISCLOSURE: The following authors have nothing to disclose: Marta Marin-Oto, Teresa Martin, Javier Godino, Marta Andres, Victoria Gil, Jose MarinNo Product/Research Disclosure Information.
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Infectious Disease Case Report Posters ISESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: MonoMAC is a rare syndrome characterized by a haplodeficiency of GATA2 gene products resulting in monocytopenia, B-cell and NK-cell lymphopenia, and an increased susceptibility to atypical infections1 Since its discovery in 2010, there have been only 28 other cases described in the literature. The lack of widespread familiarity with this disease impedes early identification and often leads to mistreatment with near-fatal consequences. Here we describe a case of MonoMAC which eluded diagnosis for over one year. ⋯ As our patient exemplifies, a heightened awareness of this new entity is important to avoid misdiagnosis and inappropriate treatment with chronic steroids given the potential of devastating iatrogenic complications.Reference #1: Vinh et al. Blood 2010;115:1519-1529DISCLOSURE: The following authors have nothing to disclose: Jason Schnack, Aarti Mittal, Ching-Fei ChangNo Product/Research Disclosure Information.
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COPD Epidemiology & Physiology PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: To identify predictors associated with hospital readmission in patients discharged after acute exacerbation of chronic obstructive lung disease (AECOPD). ⋯ The following authors have nothing to disclose: Sana' AL Aqqad, Teo Ley Khim, Irfhan Ali Hyder Ali, Balamurugan TangiisuranNo Product/Research Disclosure Information.
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Tuberculosis Case Report PostersSESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: Pulmonary tuberculosis is an ancient contagious disease which remains a public health issue due to a large reservoir of latent infection (1). ⋯ So, we should always treat tuberculosis as a life-threatening infectious disease which remains a major global health issue, especially due to dormant bacteria.Reference #1: WHO 2010. Global tuberculosis control-surveillance, planning, financing. Geneva, Switzerland: WHO.Reference #2: Allwood BW, Myer L, Bateman ED A Systematic Review of the Association between Pulmonary Tuberculosis and the Development of ChronicAirflow Obstruction in Adults. Respiration. 2013 May 3DISCLOSURE: The following authors have nothing to disclose: Bianca Paraschiv, Claudia Lucia Toma, Stefan Dumitrache-Rujinski, Liliana Grigoriu, Ionela Nicoleta Belaconi, Codin Saon, Miron Alexandru BogdanNo Product/Research Disclosure Information.
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OSA & COPD PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: To determine the prevalence of COPD in patients with OSAHS treated in a specific unit of sleep-disordered breathing. ⋯ The following authors have nothing to disclose: Elena Ojeda, Soledad Lopez, Liliana Moran, Paula Rodriguez, Irene Jarana, Pilar DeLucasNo Product/Research Disclosure Information.