Articles: chronic.
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Lung Cancer Posters ISESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Tobacco smoke exposure is the main risk factor for the development of lung cancer (LC) and chronic obstructive pulmonary disease (COPD). In turn, COPD is a risk factor for the development of LC. Tobacco smoke contains a large number of free radicals, reactive oxygen species and reactive nitrogen species that increase oxidative stress. Damage to membrane lipids (lipid peroxidation) produces different volatile organic compounds (VOC) (aldehydes, carboxylic acids, etc.) that can be detected in exhaled breath. ⋯ Propanoic acid in exhaled breath samples could be used to discriminate between lung cancer patients without and with COPD. Further studies are required to confirm this hypothesis. Supported by FIS (Formación en Investigación en Salud): PI07/1116; Neumomadrid 2008 and 2012, SEPAR (Sociedad Española de Neumonología y Cirugía Torácica) 2009/881 and 2012/135CLINICAL IMPLICATIONS: New biomrkers involved in lung cancer screening and other respiratory diseases (COPD)DISCLOSURE: The following authors have nothing to disclose: Carolin Wagner, Maria Angeles Munoz, Javier Jareño, Carlos Gutierrez Ortega, Antonio Aguilar Ros, Belen Carrillo Aranda, Jose Angel Maldonado Sanz, Concepcion Civera, Luis CallolVOCs are used in the evaluation of respiratory diseases such as lung cancer, COPD.
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Pleural CasesSESSION TYPE: Case ReportsPRESENTED ON: Sunday, March 23, 2014 at 09:00 AM - 10:00 AMINTRODUCTION: Sarcoidosis is a chronic multi-system disorder of unknown etiology characterized by granulomatous inflammation. Commonly involved organs include lymph nodes, lungs, skin, eyes and heart. Pulmonary involvement is manifested as hilar or mediastinal lymphadenopathy with parenchymal opacities. Pleural effusion and underlying pleural involvement with sarcoidosis is uncommon and is seen in less than 2% of the cases of pulmonary sarcoidosis. We present one of such case. ⋯ The following authors have nothing to disclose: Deepankar Sharma, Joshua RubenfeldNo Product/Research Disclosure Information.
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Surgery Case Report Posters ISESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: Chronic expanding thoracic hematoma (CETH) is a rare clinical entity mimicking invasive soft-tissue neoplasms in the thorax. It is reported to occur in patients with a history of trauma or surgery or tuberculosis. It is considered a form of chronic empyema and has also been designated as chronic hemorrhagic empyema. We present a case of a CETH, treated successfully with surgical resection. ⋯ The following authors have nothing to disclose: Danae Delivanis, Vanessa Yap, Daniel Fusco, Debapriya DattaNo Product/Research Disclosure Information.
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The incidence of death among patients admitted for severe sepsis or septic shock is high. Adrenomedullin (ADM) plays a central role in initiating the hyperdynamic response during the early stages of sepsis. Pilot studies indicate an association of plasma ADM with the severity of the disease. In the present study we utilized a novel sandwich immunoassay of bioactive plasma ADM in patients hospitalized with sepsis in order to assess the clinical utility. ⋯ In patients admitted with sepsis, severe sepsis or septic shock plasma ADM is strongly associated with severity of disease, vasopressor requirement and 28-day mortality.