Articles: function.
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Lung Cancer Posters ISESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Oxidative stress is increased in lung cancer (LC) and generated volatile organic compounds (VOC). We can detect VOC in exhaled breath using the analytical technique Thermal desorber-gase cromatography and mass spectrometry (TD-GC/MS). The determination of VOC, may be useful as a noninvasive screening in LC. ⋯ The following authors have nothing to disclose: Javier Jareño, Maria Angeles Munoz, Carolin Wagner, Concepcion Civera, Luis CallolNo Product/Research Disclosure Information.
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Infectious Disease Case Report Posters ISESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: MonoMAC is a rare syndrome characterized by a haplodeficiency of GATA2 gene products resulting in monocytopenia, B-cell and NK-cell lymphopenia, and an increased susceptibility to atypical infections1 Since its discovery in 2010, there have been only 28 other cases described in the literature. The lack of widespread familiarity with this disease impedes early identification and often leads to mistreatment with near-fatal consequences. Here we describe a case of MonoMAC which eluded diagnosis for over one year. ⋯ As our patient exemplifies, a heightened awareness of this new entity is important to avoid misdiagnosis and inappropriate treatment with chronic steroids given the potential of devastating iatrogenic complications.Reference #1: Vinh et al. Blood 2010;115:1519-1529DISCLOSURE: The following authors have nothing to disclose: Jason Schnack, Aarti Mittal, Ching-Fei ChangNo Product/Research Disclosure Information.
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Diffuse Lung Disease Case Report PostersSESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: Diffuse alveolar hemorrhage (DAH) is a life threatening condition; it has been associated with many etiologies, including exogenous agents or drugs. Irrespective of its causes, the clinical, radiographic, and histopathological features of DAH may be similar. Hyaluronic acid (HA) injectable gels have been available for the general market since 2003 as cosmetic dermal fillers and skin booster. It is general belief that HA is a safe product. We describe a rare case of DAH caused by the use of hyaluronic acid gels. ⋯ The following authors have nothing to disclose: Jose Basora, Ricardo Fernandez, Modesto GonzalezNo Product/Research Disclosure Information.
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Critical Care Case Report PostersSESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: First described in 1950, cerebral salt wasting syndrome (CSW) is defined by development of extracellular volume depletion due to renal sodium transport abnormality in patients with intracranial disease and normal adrenal and thyroid function [1]. The entity has been controversial and its existence debatable. ⋯ This case illustrates the need for CSW recognition as a separate entity from SIADH. Failure to make this distinction in a patient with hyponatremia who has cranial conditions could lead to unbefitting and dangerous therapy with water restriction resulting in fatal outcomes.Reference #1: Peters JP, et al. A salt-wasting syndrome associated with cerebral disease. Trans Assc Am Phys. 1950, 63:57-64Reference #2: Schwartz WB, et al. A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone. Am J Med 1957 Oct 23(4):529-42DISCLOSURE: The following authors have nothing to disclose: Anita Rajagopal, John LuciaNo Product/Research Disclosure Information.
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Pleural CasesSESSION TYPE: Case ReportsPRESENTED ON: Sunday, March 23, 2014 at 09:00 AM - 10:00 AMINTRODUCTION: Patients with large pleural effusions often experience dramatic relief from dyspnea after thoracentesis. While this is well-recognized, the physiological basis for such relief remains poorly understood. One commonly held belief is that thoracentesis allows for lung reexpansion, ventilation of previously atelectatic lung, and improved ventilation-perfusion matching, subsequently leading to dyspnea relief. This contrasts with the concept of "length-tension inappropriateness," which posits chest wall mechanics best explain dyspnea relief. ⋯ Our case established that dyspnea relief after thoracentesis likely results from changes in chest wall mechanics and/or work of breathing. This observation has direct clinical implications and could inform therapeutic decisions.Reference #1: Brown NE et al. Changes in pulmonary mechanics and gas exchange following thoracentesis. Chest. 1978; 74: 540-42Reference #2: Estenne M et al. Mechanism of relief of dyspnea after thoracentesis in patients with large pleural effusions. Am J Med. 1983; 74(5):813-9Reference #3: Wang LM et al. Improved lung function after thoracentesis in patients with paradoxical movement of a hemidiaphragm secondary to a large pleural effusion. Respirology. 2007; 12(5):719-23DISCLOSURE: The following authors have nothing to disclose: Mary Klecka, Fabien MaldonadoNo Product/Research Disclosure Information.