Articles: function.
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Mortality after lower limb amputation is high, with UK 30-day mortality rates of 9-17%. We performed a retrospective analysis of factors affecting early and late outcome after lower limb amputation for peripheral vascular disease or diabetic complications at a UK tertiary referral vascular centre between 2003 and 2010. Three hundred and thirty-nine patients (233 male), of median (IQR [range]) age 73 (62-79 [26-92]) years underwent amputation. ⋯ Anaesthetic technique was associated with long-term mortality on survival analysis (p = 0.04), but not when analysed using regression modelling. Mortality after lower limb amputation relates to patient age, ASA, out-of-hours surgery and renal dysfunction. These data support lower limb amputations' being performed during daytime hours and after modification replace with 'of ' correctable risk factors.
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This study investigates the change of endothelial cell morphology and function at the rabbit basilar bifurcations in response to sustained high blood flow after bilateral common carotid artery ligation. ⋯ This study is the first to present endothelial cell changes of basilar artery bifurcation in response to sustained high blood flow in rabbits. Endothelial cell impairment possibly initiates aneurysm formation.
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COPD Case Report PostersSESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: A giant bulla is defined as an air space in the lung that occupies at least 30% of the hemithorax. Indications for surgical resection are controversial but most commonly include dypnea due to compression of adjacent lung tissue or spontaneous pneumothorax. Previous authors have suggested including mediastinal shift as an indication, but outcome data is lacking. We present a unique case of a 71-year-old patient with bullous emphysema which resulted in compression of the dextrocardial structures. ⋯ The following authors have nothing to disclose: B. Jakub Wilhelm, Aniket Sakharpe, Leopoldo Baccaro, Stanley Ogu, Richard AngelicoNo Product/Research Disclosure Information.
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Critical CareSESSION TYPE: Slide PresentationPRESENTED ON: Saturday, March 22, 2014 at 04:15 PM - 05:15 PMPURPOSE: Non invasive ventilation (NIV) is a standardized treatment that has proven beneficial effects in different respiratory and cardiologic diseases. The increasing development of NIV has enabled chest physicians to assist more complex patients and stimulate the setting-up of specials units (Respiratory High-Dependency Care Units [RHDCU]). These units are specialized in severe respiratory patients who need NIV and monitoring. The aim of this study was to evaluate the impact of a RHDCU in non-invasive ventilated patients. ⋯ The following authors have nothing to disclose: Alejandro Peralta, Lucia Gimeno, Cristina Oliver, Alicia Binimelis, Belen Nuñez, Miguel Carrera, Monica de la Peña, Ernest SalaNo Product/Research Disclosure Information.
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DVT/PE PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: As the benefits of thrombolytic therapy in patients with pulmonary embolism, with a normal blood pressure and intermediate clinical risk, as determined by right ventricular dysfunction on echocardiography or elevated serum markers of cardiac necrosis, are uncertain, an audit of patients diagnosed with acute PE using MDCTPA was performed to determine the mortality and hemorrhagic complications in-hospital and at 30 days. ⋯ The following authors have nothing to disclose: Carla Nobre, Dinis Mesquita, Boban ThomasNo Product/Research Disclosure Information.