Articles: function.
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Pulmonary Hypertension Posters IISESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: The prevalence of PAH in patients with IPF is not well known. There has been no prospective study to date. The purpose of our study was to know the prevalence of PAH in patients with IPF at any stage of severity ⋯ 60 patients (18 women, age at diagnosis 64 years) were included and 56 completed the study protocol. Patient characteristics: FVC 64%, DLCO 41%, 6MWT 357 meters, systolic pulmonary arterial pressure 46 mmHg. 17 patients showed a systolic pulmonary artery pressure greater than 40 mmHg and in 14 of them PAH was confirmed by right heart catheterization with a mean pulmonary arterial pressure of 28.6 mmHg. When comparing various clinical and functional parameters between patients with and without PAH significant differences were seen in FVC, FEV1, DLCO, 6MWT and Functional Class. In a multivariate analysis DLCO was associated with the presence of PAHCONCLUSIONS: PAH is not infrequent in patients with IPF (around 26%).Patients with more severe disease are more likely to develop PAH. A marked decrease in DLCO is independently associated with the presence of PAHCLINICAL IMPLICATIONS: PAH is a devastating disease with prognostic and therapeutic implications in patients with IPF. To know the prevalence and associated factors in very important for a better management of this patients because we now have effective treatments in PAHDISCLOSURE: The following authors have nothing to disclose: Adolfo Villar, Julio Ancochea, Antonio XaubetNo Product/Research Disclosure Information.
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TransplantationSESSION TYPE: Slide PresentationsPRESENTED ON: Sunday, March 23, 2014 at 12:15 PM - 01:15 PMPURPOSE: Maintenance immunosuppression regimens to prevent lung allograft rejection include a calcineurin inhibitor (tacrolimus or cyclosporine A), which can gradually cause renal damage and impaired function, and other factors (diabetes or systemic hypertension), if present, can also contribute to progressive renal insufficiency. Lung transplant (LTX) recipients who develop profound renal dysfunction due to Stage IV kidney disease may be candidates for orthotopic kidney transplantation. We conducted a chart review to evaluate the outcomes of patients who underwent renal transplantation (RTX) for end-stage renal insufficiency associated with prior LTX to determine safety and efficacy and to identify significant complications. ⋯ The following authors have nothing to disclose: Ted McMenomy, Mehgan Holland, Keith MeyerNo Product/Research Disclosure Information.
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Slide PresentationsPRESENTED ON: Saturday, March 22, 2014 at 12:15 PM - 01:15 PMPURPOSE: The relationship between maximal cardiopulmonary exercise testing (CPX) and submaximal exercise in patients with idiopathic pulmonary fibrosis (IPF) is poorly understood. CPX and the 6-minute walk test (6MWT) were compared with a focus on exercise tolerance (ET) and systemic oxidant stress (OS) in patients with IPF. ⋯ The following authors have nothing to disclose: Lawrence Cahalin, Carol Ramos, Ignacio Gaunaurd, Nicole Eustis, Constanza Sol, Meryl Cohen, Orlando Gomez-Marin, Diana Cardenas, Robert JacksonNo Product/Research Disclosure Information.
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Cancer Case Report Posters IISESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: Inflammatory psedotumor of the lung is a rare, quasineoplastic lung tumor of unknown etiology. It occurs most often in young adults ⋯ Although pulmonary inflammatory pseudotumors are considered benign, they can be very aggressive locally or cause metastasis. The differential diagnosis is usually with lung cancer and the deffinitive diagnosis is made on histopathological exam. If possible, complete surgical resection is necessary and can cure the disease. Extended follow-up is required in these patients.Reference #1: Surgical management of pulmonary inflammatory pseudotumors: a single center experience. Mondello B, Lentini S, Barone M, Barresi P, Monaco F, Familiari D, La Rocca A, Sibilio M, Acri IE, David A, Monaco M. J Cardiothorac Surg. 2011 Feb 23;6:18. doi: 10.1186/1749-8090-6-18. PMID:21345228DISCLOSURE: The following authors have nothing to disclose: Ionela Belaconi, Claudia Toma, Stefan Dumitrache-Rujinski, Alina Croitoru, Miron BogdanNo Product/Research Disclosure Information.
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Bronchiectasis PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Low spirometry values are associated with increased risk for an exacerbation in patients with Chronic Obstructive Pulmonary Disease. There is paucity of data regarding patients with non-CF bronchiectasis. We endeavored to examine the possible relation between non-CF bronchiectasis exacerbations and pulmonary function tests. ⋯ The following authors have nothing to disclose: Evangelos Balis, Eugenios Metaxas, Joseph Papaparaskevas, Despina Chrysovergi, Nikos Spanakis, Athanasios Tsakris, Georgios TatsisNo Product/Research Disclosure Information.